Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17028058 | 0.81 | HDAC6 (0.61) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL25381348 | 0.75 | GAA (0.53) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7989152 | 0.73 | HDAC1 (0.77) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4508472 | 0.73 | CES2 (0.64) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1147702 | 0.73 | KDM4E (0.73) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL231897 | 0.72 | KDR (0.78) | NPC1RAB9ASMN1; SMN2HDAC6PKM | |
| SCHEMBL4522324 | 0.72 | HDAC1 (0.69) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9384187 | 0.72 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL1422257 | 0.71 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1412816 | 0.71 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | claimed |
| EP-4238972-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer AG (DE) | 2023-09-06 | — | — | EP | claimed |
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | disclosed |
| EP-4238972-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer AG (DE) | 2023-09-06 | — | — | EP | disclosed |
| EP-4238972-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer AG (DE) | 2023-09-06 | — | — | EP | disclosed |