Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24299348 | 0.91 | CRBN (0.66) | CRBNARCDK9DDB1ESR1 | |
| SCHEMBL29986989 | 0.91 | CRBN (0.66) | CRBNARCDK9DDB1ESR1 | |
| SCHEMBL31447732 | 0.89 | CRBN (0.80) | CRBNARCDK9DDB1ALDH1A1 | |
| SCHEMBL29927999 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ALK | |
| SCHEMBL29132201 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ALK | |
| SCHEMBL29132302 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ALDH1A1 | |
| SCHEMBL23268079 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ALDH1A1 | |
| SCHEMBL24819369 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ALDH1A1 | |
| SCHEMBL29260077 | 0.89 | CRBN (0.69) | CRBNARCDK9DDB1ESR1 | |
| SCHEMBL20046436 | 0.89 | CRBN (0.74) | CRBNARCDK9DDB1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257365-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257365-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | CRBN 610/4885AR 1/4885CDK9 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.