SCHEMBL25385484

SCHEMBL25385484

[CH2]CCC(C)CCCCCCC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
ACE2 Q9BYF1 1/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25386499 1.00 LMNA (0.37) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25384365 0.98 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25384623 0.91 LMNA (0.37) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25385064 0.91 MEN1 (0.42) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25385224 0.89 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25386382 0.89 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25384021 0.87 MEN1 (0.40) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL25384577 0.84 MEN1 (0.41) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL19664758 0.84 MEN1 (0.33) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL19664763 0.84 MEN1 (0.33) LMNAMEN1CYP3A4ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024252-A1 LIPID NANOPARTICLE NITTO DENKO CORPORATION (JP) 2024-01-25 US disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2023191050-A1 PHARMACEUTICAL COMPOSITION FOR DELIVERY TO CANCER, OR IMMUNOSTIMULATING COMPOSITION 日東電工株式会社 2023-10-05 WO disclosed
WO-2023188830-A1 LIPID NANOPARTICLES 国立大学法人北海道大学 2023-10-05 WO disclosed
EP-4223314-A1 LIPID NANOPARTICLE National University Corporation Hokkaido University (JP) 2023-08-09 EP disclosed
CN-116367718-A Lipid nanoparticles 国立大学法人北海道大学 2023-06-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024252-A1 LIPID NANOPARTICLE LIPC, ACOX1, ABCB4 LMNA 1094/4885MEN1 3041/4885CYP3A4 1117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.