Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543776 | 0.78 | ACHE (0.40) | ACHEMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL20241590 | 0.72 | KMT2A (0.47) | TEAD4ACHEHTR7KMT2A | |
| SCHEMBL12895543 | 0.72 | DYRK1A (0.38) | NR3C2MEN1KMT2A | |
| SCHEMBL12883363 | 0.71 | TYK2 (0.39) | NR3C2MEN1KMT2A | |
| SCHEMBL2118728 | 0.69 | NOS3 (0.64) | MEN1KMT2A | |
| SCHEMBL29883563 | 0.69 | NOS3 (0.64) | MEN1KMT2A | |
| SCHEMBL13036454 | 0.69 | NR3C2 (0.49) | NR3C2MEN1KMT2ASMN1; SMN2 | |
| Alcohol SCHEMBL14813490 | 0.68 | KDM4E (0.54) | TEAD4P4HBMAPTSMN1; SMN2 | |
| SCHEMBL28056162 | 0.67 | MAOA (0.44) | — | |
| SCHEMBL20241559 | 0.66 | ACHE (0.65) | ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693555-A | Imidazopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160475-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-08-31 | — | — | WO | disclosed |