Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386647 | 1.00 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2AALDH1A1 | |
| SCHEMBL31595489 | 1.00 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2AALDH1A1 | |
| SCHEMBL30567131 | 1.00 | MTNR1B (0.53) | MTNR1BPYGMMEN1KMT2AALDH1A1 | |
| SCHEMBL31595464 | 0.91 | L3MBTL1 (0.55) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL25386868 | 0.91 | L3MBTL1 (0.55) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL31256617 | 0.91 | L3MBTL1 (0.55) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL25386863 | 0.91 | L3MBTL1 (0.55) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL25388461 | 0.87 | MTNR1B (0.62) | MTNR1BPYGMMEN1KMT2AALDH1A1 | |
| SCHEMBL25387001 | 0.84 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2AALDH1A1 | |
| SCHEMBL25386999 | 0.84 | MTNR1B (0.52) | MTNR1BPYGMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |