Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386868 | 1.00 | L3MBTL1 (0.55) | L3MBTL1LMNAPOLBRAB9ATDP1 | |
| SCHEMBL25386863 | 1.00 | L3MBTL1 (0.55) | L3MBTL1LMNAPOLBRAB9ATDP1 | |
| SCHEMBL31256617 | 1.00 | L3MBTL1 (0.55) | L3MBTL1LMNAPOLBRAB9ATDP1 | |
| SCHEMBL31595489 | 0.91 | MTNR1B (0.53) | L3MBTL1LMNAPOLBRAB9AMEN1 | |
| SCHEMBL25386647 | 0.91 | MTNR1B (0.53) | L3MBTL1LMNAPOLBRAB9AMEN1 | |
| SCHEMBL30567131 | 0.91 | MTNR1B (0.53) | L3MBTL1LMNAPOLBRAB9AMEN1 | |
| SCHEMBL25386646 | 0.91 | MTNR1B (0.53) | L3MBTL1LMNAPOLBRAB9AMEN1 | |
| SCHEMBL25384652 | 0.89 | MEN1 (0.53) | L3MBTL1LMNAPOLBRAB9ATDP1 | |
| SCHEMBL25384654 | 0.89 | MEN1 (0.53) | L3MBTL1LMNAPOLBRAB9ATDP1 | |
| SCHEMBL25387247 | 0.89 | MEN1 (0.53) | L3MBTL1LMNAPOLBRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | UNITED STATES GOVERNMENT | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | PCNA, MKI67, PCLAF | L3MBTL1 1817/4885LMNA 1607/4885POLB 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.