SCHEMBL25388967

SCHEMBL25388967

CC(C)CNC(=O)C(C)(C)N1CCN(c2ccccc2F)CC1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 3/20 0.47
TSHR P16473 5/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
TP53 P04637 2/20 0.46
HSD17B10 Q99714 3/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
ALOX15 P16050 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25388961 0.91 LMNA (0.40) SMN1; SMN2KDM4ETSHRLMNAMAPT
SCHEMBL25389772 0.88 GPR119 (0.39) SMN1; SMN2KDM4ETSHRLMNAMAPT
SCHEMBL26238724 0.86 ADRA1A (0.43) TSHRLMNAMAPTALDH1A1
SCHEMBL26238713 0.86 LMNA (0.42) SMN1; SMN2KDM4ETSHRLMNAKMT2A
SCHEMBL26238734 0.86 AKR1C3 (0.46)
SCHEMBL26238705 0.86 KDM4E (0.39) SMN1; SMN2KDM4ELMNAMAPTTP53
SCHEMBL26238630 0.86 KDM4E (0.42) SMN1; SMN2KDM4ELMNAMAPTKMT2A
SCHEMBL25387649 0.86 BDKRB1 (0.43) TSHRLMNAMAPTKMT2ACYP2C9
SCHEMBL25387883 0.85 MAPT (0.41) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1
SCHEMBL25389204 0.85 GPR119 (0.39) SMN1; SMN2KDM4ETSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 SMN1; SMN2 1171/4885KDM4E 4072/4885TSHR 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.