Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344078 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPK1SMN1; SMN2SCN10AKDM4E | |
| SCHEMBL31343943 | 0.86 | SCN10A (0.45) | ALDH1A1MAPK1SMN1; SMN2SCN10AFABP3 | |
| SCHEMBL31343874 | 0.85 | SCN10A (0.40) | ALDH1A1MAPK1SMN1; SMN2SCN10AKDM4E | |
| SCHEMBL25388683 | 0.83 | SCN10A (0.44) | ALDH1A1MAPK1SMN1; SMN2SCN10AKDM4E | |
| SCHEMBL30562528 | 0.83 | SCN10A (0.44) | ALDH1A1MAPK1SMN1; SMN2SCN10AKDM4E | |
| SCHEMBL31343925 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2SCN10AKDM4E | |
| SCHEMBL25389487 | 0.77 | KMT2A (0.40) | ALDH1A1MAPK1SMN1; SMN2SCN10AHPGD | |
| SCHEMBL25389483 | 0.75 | RBP4 (0.44) | SCN10ARBP4KMT2AKIF18A | |
| SCHEMBL16149339 | 0.75 | SCN10A (0.45) | ALDH1A1MAPK1SMN1; SMN2SCN10AHSD17B10 | |
| SCHEMBL21906092 | 0.73 | SCN10A (0.56) | ALDH1A1SCN10AFABP3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025029890-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |