Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352131 | 0.77 | OGT (0.53) | OGTMCL1NOS1NOS3NOS2 | |
| SCHEMBL221702 | 0.73 | OGT (0.53) | OGTMCL1NOS1NOS3NOS2 | |
| SCHEMBL1461411 | 0.73 | KDM4E (0.33) | LMNA | |
| Carsalam SCHEMBL26521 | 0.72 | OGT (0.57) | OGTMCL1LMNACYP1A2BLM | |
| Carsalam SCHEMBL2332292 | 0.71 | OGT (0.55) | OGTMCL1LMNACYP1A2BLM | |
| Carsalam SCHEMBL5149682 | 0.71 | OGT (0.55) | OGTMCL1LMNACYP1A2BLM | |
| SCHEMBL467966 | 0.68 | HSD17B3 (0.49) | CYP1A2 | |
| SCHEMBL694630 | 0.67 | MAOA (0.67) | LMNA | |
| SCHEMBL2289312 | 0.67 | NOS1 (0.62) | NOS1NOS3NOS2LMNA | |
| SCHEMBL1071182 | 0.67 | DAO (0.58) | MCL1NOS1NOS3NOS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173053-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |