SCHEMBL2289312

SCHEMBL2289312

Cc1ccc2c(=O)[nH]c(=O)oc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.62
NOS3 P29474 2/20 0.58
NOS2 P35228 2/20 0.58
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 1/20 0.47
MAOB P27338 1/20 0.41
CDC25A P30304 1/20 0.41
CDC25C P30307 1/20 0.41
LMNA P02545 2/20 0.41
PSMB8 P28062 1/20 0.41
KEAP1 Q14145 1/20 0.41
POLB P06746 3/20 0.39
KMT2A Q03164 2/20 0.39
ALPL P05186 1/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
MEN1 O00255 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CHEK1 O14757 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6230934 0.85 NOS1 (0.62) NOS1NOS3NOS2ALDH1A1HPGD
SCHEMBL25394296 0.78 KDM4E (0.55) ALDH1A1GAAHPGDMAOBLMNA
SCHEMBL6590835 0.78 MAOB (0.45) ALDH1A1MAOBCDC25ACDC25CLMNA
SCHEMBL8777948 0.78 KDM4E (0.50) NOS1NOS3NOS2ALDH1A1GAA
SCHEMBL1500233 0.78 METAP2 (0.43) NOS1NOS3NOS2LMNACHEK1
SCHEMBL1071182 0.78 DAO (0.58) NOS1NOS3NOS2CDC25ACDC25C
SCHEMBL2284104 0.77 KDM4E (0.57) ALDH1A1GAAHPGDMAOBLMNA
SCHEMBL244119 0.77 NOS1 (1.00) NOS1NOS3NOS2ALDH1A1GAA
SCHEMBL31124704 0.74 ALDH1A1 (0.55) NOS1NOS3NOS2ALDH1A1GAA
SCHEMBL8175559 0.74 ALDH1A1 (0.55) NOS1NOS3NOS2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348296-B2 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2008-03-25 US claimed
EP-1245403-B1 Thermographic recording material with improved image tone. AGFA GEVAERT (BE) 2007-01-03 EP claimed
EP-1431059-B1 Barrier layers for use in substantially light-insensitive thermographic recording materials AGFA GEVAERT (BE) 2006-08-02 EP claimed
US-7045487-B2 Toning agents for use in substantially light-insensitive recording materials AGFA GEVAERT (BE) 2006-05-16 US claimed
EP-1431814-B1 Toning agents for use in substantially light-insensitive recording materials. AGFA GEVAERT (BE) 2006-04-26 EP claimed
US-7033743-B2 Barrier layers for use in substantially light-insensitive thermographic recording materials AGFA GEVAERT (BE) 2006-04-25 US claimed
US-7018786-B2 Toning agents for use in thermographic recording materials AGFA GEVAERT (BE) 2006-03-28 US claimed
US-20050003298-A1 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2005-01-06 US claimed
US-20050003315-A1 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2005-01-06 US claimed
EP-1484641-A1 Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials. Agfa-Gevaert (BE) 2004-12-08 EP claimed
US-6677274-B2 CONTAINING SILVER BEHENATE INCLUDING PHASE I SILVER BEHENATE, A REDUCING AGENT THEREFOR IN THERMAL WORKING RELATIONSHIP THEREWITH AND A BINDER AGFA-GEVAERT (BE) 2004-01-13 US claimed
US-20030186809-A1 Thermographic recording material with improved image tone AGFA-GEVAERT (BE) 2003-10-02 US claimed
US-20030064891-A1 Thermographic recording material with improved image tone AGFA-GEVAERT (BE) 2003-04-03 US claimed
US-20030054958-A1 Thermographic recording material with improved print archivability without loss in printability AGFA-GEVAERT (BE) 2003-03-20 US claimed
EP-1270255-A1 Thermographic recording material with improved image tone Agfa-Gevaert (BE) 2003-01-02 EP claimed
EP-1245403-A1 Thermographic recording material with improved image tone. Agfa-Gevaert (BE) 2002-10-02 EP claimed
EP-1245404-A1 Thermographic recording material providing prints with good image density and tone having improved archivability Agfa-Gevaert (BE) 2002-10-02 EP claimed
US-20020052294-A1 Thermographic recording material with improved image tone AGFA HEALTHCARE N.V. (BE) 2002-05-02 US claimed
US-6337303-B1 MULTISTAGE PROCESS LAYER, LIGHT INSENSITIVE BLACK AND WHITE THERMOGRAPHIC RECORDING MATERIAL AND THERMOSENSITIVE ELEMENT,ORGANOSILVER SALT WITH REDUCING AGENT, 3,5-DIHYDROXYBENZOIC ACID AGFA-GEVAERT (BE) 2002-01-08 US claimed
EP-1059560-A1 Thermographic recording material with improved image tone AGFA-GEVAERT N.V. (BE) 2000-12-13 EP claimed