Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516114 | 0.86 | MEN1 (0.48) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2465651 | 0.85 | HPGD (0.46) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2468744 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2468948 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2464573 | 0.82 | NPC1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL2469014 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2467907 | 0.80 | NPC1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL18797967 | 0.78 | MAPT (0.49) | SMN1; SMN2NPC1RAB9AATMMEN1 | |
| SCHEMBL2466802 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL6755639 | 0.77 | ALDH1A1 (0.71) | ALDH1A1ALOX12SMN1; SMN2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| US-8466081-B2 | Halogenated amide ester and internal electron donor with same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | ALDH1A1 701/4885ALOX12 249/4885SMN1; SMN2 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.