Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462152 | 0.88 | GPR139 (0.52) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL14243987 | 0.85 | SLC6A9 (0.48) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2465585 | 0.85 | SLC6A9 (0.46) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2464590 | 0.84 | NPC1 (0.48) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2539486 | 0.82 | ALDH1A1 (0.47) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2465537 | 0.82 | NPC1 (0.51) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2467907 | 0.81 | NPC1 (0.53) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2465651 | 0.79 | HPGD (0.46) | NPC1SLC6A9RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2465539 | 0.79 | NPC1 (0.50) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2466812 | 0.79 | SLC6A9 (0.47) | NPC1SLC6A9SLC6A5RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| US-8466081-B2 | Halogenated amide ester and internal electron donor with same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | NPC1 299/4885SLC6A9 963/4885SLC6A5 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.