Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 10/20 | 0.38 |
| ▸ | RAB9A | P51151 | 10/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395244 | 1.00 | HDAC1 (0.48) | HDAC1HDAC2PKMNPC1RAB9A | |
| SCHEMBL9605459 | 0.75 | HDAC1 (0.48) | HDAC1HDAC2PKMNPC1RAB9A | |
| SCHEMBL25393170 | 0.75 | GAA (0.36) | PKMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL25393166 | 0.75 | GAA (0.36) | PKMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18851551 | 0.73 | HDAC1 (0.49) | HDAC1HDAC2PKMNPC1RAB9A | |
| SCHEMBL7239055 | 0.72 | GRM4 (0.53) | PKMNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL7239050 | 0.72 | GRM4 (0.53) | PKMNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL871327 | 0.70 | PTGS1 (0.51) | HDAC1HDAC2PKMNPC1RAB9A | |
| SCHEMBL27899681 | 0.70 | PTGS1 (0.47) | HDAC1HDAC2PKMNPC1RAB9A | |
| SCHEMBL15033460 | 0.70 | PDE10A (0.55) | HDAC1HDAC2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | HDAC1 4230/4885HDAC2 4413/4885PKM 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.