Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25393170 | 1.00 | GAA (0.36) | GAAPKMMAPTSMN1; SMN2RAB9A | |
| SCHEMBL25395239 | 0.75 | HDAC1 (0.48) | PKMMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25395244 | 0.75 | HDAC1 (0.48) | PKMMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25392292 | 0.72 | ALDH1A1 (0.53) | PKMMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25392297 | 0.72 | ALDH1A1 (0.53) | PKMMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL870663 | 0.71 | GAA (0.48) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25392186 | 0.71 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL25392190 | 0.71 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL3485651 | 0.69 | RAB9A (0.48) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23384762 | 0.69 | GAA (0.42) | GAAMAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | GAA 485/4885PKM 4202/4885MAPT 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.