SCHEMBL25395706

SCHEMBL25395706

O=C(O)c1cc(C(=O)O)cc(-c2c3nc(c(-c4c(Br)cccc4Br)c4ccc([nH]4)c(-c4cc(C(=O)O)cc(C(=O)O)c4)c4nc(c(-c5c(Br)cccc5Br)c5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CYCS P99999 4/20 0.67
▸ TOP1 P11387 3/20 0.59
▸ ENPP2 Q13822 1/20 0.41
▸ ABCG2 Q9UNQ0 1/20 0.39
▸ TERT O14746 3/20 0.38
▸ STAT3 P40763 1/20 0.38
▸ STAT1 P42224 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14246889 0.88 CYCS (0.83) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL29684505 0.88 CYCS (0.83) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL30999674 0.85 CYCS (0.80) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL26089781 0.84 CYCS (0.78) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL30493187 0.81 TOP1 (0.68) CYCSTOP1ENPP2TERTSTAT3
SCHEMBL25395955 0.81 TOP1 (0.68) CYCSTOP1ENPP2TERTSTAT3
SCHEMBL12842182 0.81 CYCS (0.97) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL5013893 0.81 TOP1 (0.51) CYCSTOP1ENPP2TERTSTAT3
SCHEMBL28499238 0.80 CYCS (0.67) CYCSTOP1ENPP2STAT3STAT1
SCHEMBL28479053 0.80 CYCS (0.67) CYCSTOP1ENPP2TERTSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546743-B2 Electrochemical sensor and related methods UNIVERSITY OF SOUTH FLORIDA (US) 2026-02-10 — — US disclosed
US-20230296554-A1 ELECTROCHEMICAL SENSOR AND RELATED METHODS UNIVERSITY OF SOUTH FLORIDA 2023-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12546743-B2 Electrochemical sensor and related methods EPX, MUC1, EPCAM CYCS 2095/4885TOP1 4862/4885ENPP2 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback