Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 10/20 | 1.00 |
| ▸ | IGF1R | P08069 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | MYC | P01106 | 1/20 | 0.77 |
| ▸ | MAX | P61244 | 1/20 | 0.77 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539566 | 1.00 | PIM1 (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL2539569 | 1.00 | PIM1 (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL22971869 | 0.87 | CISD1 (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL10042186 | 0.87 | MYC (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL346694 | 0.87 | MYC (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL346693 | 0.87 | MYC (1.00) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL8186366 | 0.87 | PIM1 (0.77) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL8186364 | 0.87 | PIM1 (0.77) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL8185473 | 0.85 | IGF1R (0.74) | PIM1PIM2IGF1RRAB9ANPC1 | |
| SCHEMBL8185477 | 0.85 | IGF1R (0.74) | PIM1PIM2IGF1RRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263664-A1 | Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2011-10-27 | — | — | US | claimed |
| EP-2217235-A2 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | Musc Foundation for Research Development (US) | 2010-08-18 | — | — | EP | claimed |
| WO-2009064486-A9 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2009064486-A2 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2009-05-22 | — | — | WO | claimed |
| WO-2025064325-A1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES, INC. (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |
| US-9242944-B2 | Potent analogues of the C-Myc inhibitor 10074-G5 with improved cell permeability | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-01-26 | — | — | US | disclosed |
| US-20140296307-A1 | POTENT ANALOGUES OF THE C-MYC INHIBITOR 10074-G5 WITH IMPROVED CELL PERMEABILITY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-10-02 | — | — | US | disclosed |
| US-20110263664-A1 | Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2217235-A2 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | Musc Foundation for Research Development (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009064486-A9 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009064486-A2 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296307-A1 | POTENT ANALOGUES OF THE C-MYC INHIBITOR 10074-G5 WITH IMPROVED CELL PERMEABILITY | MYC, MYCBP, MKI67 | PIM1 62/4885PIM2 146/4885IGF1R 461/4885 |
| US-20110263664-A1 | Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer | PIM1, PIM2, PIM3 | PIM1 1/4885PIM2 2/4885IGF1R 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.