SCHEMBL10042186

SCHEMBL10042186

CCc1ccc(/C=C2/SC(=S)NC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 3/20 1.00
MAX P61244 3/20 1.00
NPC1 O15118 1/20 1.00
RAB9A P51151 1/20 1.00
IGF1R P08069 1/20 0.77
PIM1 P11309 1/20 0.77
PIM2 Q9P1W9 1/20 0.77
CRHBP P24387 2/20 0.68
CRHR2 Q13324 2/20 0.68
NAT1 P18440 5/20 0.66
CISD1 Q9NZ45 4/20 0.66
CSNK2A2 P19784 1/20 0.65
CLK1 P49759 1/20 0.65
CSNK2B P67870 1/20 0.65
CSNK2A1 P68400 1/20 0.65
DYRK1A Q13627 1/20 0.65
DYRK1B Q9Y463 1/20 0.65
CA2 P00918 1/20 0.65
EPHX1 P07099 1/20 0.65
MAOA P21397 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346693 1.00 MYC (1.00) MYCMAXNPC1RAB9AIGF1R
SCHEMBL346694 1.00 MYC (1.00) MYCMAXNPC1RAB9AIGF1R
SCHEMBL4051343 0.89 NPC1 (0.79) MYCMAXNPC1RAB9ACISD1
SCHEMBL4051348 0.89 NPC1 (0.79) MYCMAXNPC1RAB9ACISD1
SCHEMBL2539569 0.87 PIM1 (1.00) MYCMAXNPC1RAB9AIGF1R
SCHEMBL2539566 0.87 PIM1 (1.00) MYCMAXNPC1RAB9AIGF1R
SCHEMBL2539573 0.87 PIM1 (1.00) MYCMAXNPC1RAB9AIGF1R
SCHEMBL27412991 0.85 MYC (0.74) MYCMAXNPC1RAB9ACRHBP
SCHEMBL8172749 0.84 MYC (0.73) MYCMAXNPC1RAB9AIGF1R
SCHEMBL8172752 0.84 MYC (0.73) MYCMAXNPC1RAB9AIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119424641-A New application of RTKs/RAS/RAF/c-Myc signal channel inhibitor 哈尔滨工业大学 2025-02-14 CN claimed
US-20240360417-A1 CELL THERAPEUTIC AGENT FOR CANCER TREATMENT AND COMBINATION THERAPY WITH SAME CELL&BRAIN CO LTD (KR) 2024-10-31 US claimed
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 US claimed
CN-118512443-A Application of compound 10058-F4 in preparation of medicine for preventing and treating pseudorabies virus infection 浙江农林大学 2024-08-20 CN claimed
US-20240000935-A1 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME GENEIUS BIOTECHNOLOGY, INC. (US) 2024-01-04 US claimed
EP-4251177-A2 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME Geneius Biotechnology, Inc. (US) 2023-10-04 EP claimed
WO-2022115641-A2 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME GENEIUS BIOTECHNOLOGY, INC. (US) 2022-06-02 WO claimed
US-20220111044-A1 WHOLE CELL TUMOR VACCINES AND METHODS OF USE THEROF CHILDREN'S NATIONAL MEDICAL CENTER 2022-04-14 US claimed
WO-2013163454-A2 PSYLLID ATTRACTANTS AND THEIR USES INSCENT, INC. (US) 2013-10-31 WO claimed
US-12630883-B2 Test method of dividing blastic plasmacytoid dendritic cell neoplasm (BPDCN) into subtypes JAPANESE FOUNDATION FOR CANCER RESEARCH (JP) 2026-05-19 US disclosed
US-20260132471-A1 GENOMIC BIOMARKERS OF EARLY RECURRENCE IN COLORECTAL CANCER (CRC) FOUNDATION MEDICINE, INC. (US) 2026-05-14 US disclosed
EP-4740951-A2 IGH REARRANGEMENTS AND USES THEREOF Foundation Medicine, Inc. (US) 2026-05-13 EP disclosed
US-20260108514-A1 METHOD OF INHIBITING EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER METASTASIS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2026-04-23 US disclosed
US-12605374-B2 Methods for drug screening and compositions useful for the inhibition of cell proliferation and/or cell survival THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2026-04-21 US disclosed
WO-2013163454-A2 PSYLLID ATTRACTANTS AND THEIR USES INSCENT, INC. (US) 2013-10-31 WO disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 US disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 US disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 US disclosed
WO-2013152193-A2 METHODS OF TREATING PROLIFERATIVE DISORDERS WITH MALATE OR DERIVATIVES THEREOF BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2013-10-10 WO disclosed
US-20120015989-A1 LINKED MYC-MAX SMALL MOLECULE INHIBITORS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605374-B2 Methods for drug screening and compositions useful for the inhibition of cell proliferation and/or cell survival MKI67, DUSP10, MCL1 MYC 2960/4885MAX 3759/4885NPC1 474/4885
US-20260108514-A1 METHOD OF INHIBITING EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER METASTASIS HDAC5, HDAC6, GSK3B MYC 1085/4885MAX 3010/4885NPC1 1646/4885
US-20130287727-A1 Psyllid Attractants and Their Uses L3MBTL3, LPAR3, LPXN MYC 1550/4885MAX 1867/4885NPC1 3023/4885
US-20120015989-A1 LINKED MYC-MAX SMALL MOLECULE INHIBITORS MYC, MAX, MYCBP MYC 1/4885MAX 2/4885NPC1 2586/4885
US-12630883-B2 Test method of dividing blastic plasmacytoid dendritic cell neoplasm (BPDCN) into subtypes BCL3, BRD4, BCL6 MYC 25/4885MAX 3679/4885NPC1 3009/4885
US-12083185-B2 Small polymeric carriers for delivery of agents CD44, PGF, SLC46A1 MYC 2759/4885MAX 4299/4885NPC1 781/4885
US-20260132471-A1 GENOMIC BIOMARKERS OF EARLY RECURRENCE IN COLORECTAL CANCER (CRC) MSH2, MSH6, PMS2 MYC 322/4885MAX 1985/4885NPC1 4626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.