Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590486 | 1.00 | POLB (0.40) | POLBGAAAKR1C3AKR1C2KMT2A | |
| SCHEMBL25396029 | 0.84 | KMT2A (0.35) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL20224687 | 0.81 | NPY5R (0.41) | POLBGAAAKR1C3KMT2AMEN1 | |
| SCHEMBL25396793 | 0.80 | BRD4 (0.41) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL18319142 | 0.77 | LMNA (0.37) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL19277294 | 0.77 | LMNA (0.37) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL28508116 | 0.77 | LMNA (0.37) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL25397572 | 0.76 | KMT2A (0.36) | AKR1C3AKR1C2KMT2ANPC1RAB9A | |
| SCHEMBL25087123 | 0.75 | SMN1; SMN2 (0.35) | POLBGAAKMT2AMEN1NPC1 | |
| SCHEMBL2319362 | 0.75 | ALDH1A1 (0.39) | POLBAKR1C3AKR1C2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |