Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | CDA | P32320 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19277294 | 1.00 | LMNA (0.37) | LMNACYP2C9AKR1C3AKR1C2KMT2A | |
| SCHEMBL18319142 | 1.00 | LMNA (0.37) | LMNACYP2C9AKR1C3AKR1C2KMT2A | |
| SCHEMBL27106788 | 0.88 | KMT2A (0.42) | LMNACYP2C9AKR1C3KMT2AMEN1 | |
| SCHEMBL27106792 | 0.88 | KMT2A (0.42) | LMNACYP2C9AKR1C3KMT2AMEN1 | |
| SCHEMBL31655180 | 0.79 | KMT2A (0.38) | LMNACYP2C9AKR1C3KMT2AMEN1 | |
| SCHEMBL17185327 | 0.78 | AKR1C3 (0.32) | AKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL21740357 | 0.78 | RAB9A (0.34) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL21739122 | 0.78 | RAB9A (0.34) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL19276941 | 0.78 | RAB9A (0.34) | AKR1C3AKR1C2KMT2AMEN1NPC1 | |
| SCHEMBL25396281 | 0.77 | POLB (0.40) | AKR1C3AKR1C2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884103-B | Tricyclic compounds as immunomodulators | 正大天晴药业集团股份有限公司 | 2021-01-15 | — | — | CN | disclosed |