Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391696 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNACYP19A1HSP90AB1ALOX5 | |
| SCHEMBL18925197 | 0.72 | CYP19A1 (0.55) | ALDH1A1LMNACYP19A1PTGS2ALOX5 | |
| SCHEMBL2193198 | 0.70 | CYP19A1 (0.53) | ALDH1A1LMNACYP19A1HSP90AB1ALOX5 | |
| SCHEMBL12203590 | 0.70 | CYP19A1 (0.56) | ALDH1A1LMNACYP19A1HSP90AB1NPC1 | |
| SCHEMBL937308 | 0.70 | CYP19A1 (0.56) | ALDH1A1LMNACYP19A1HSP90AB1MEN1 | |
| SCHEMBL29230705 | 0.70 | ALDH1A1 (0.49) | ALDH1A1LMNACYP19A1PTGS2HSP90AB1 | |
| SCHEMBL15055622 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LMNACYP19A1HSP90AB1MEN1 | |
| SCHEMBL23038469 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LMNACYP19A1PTGS2HSP90AB1 | |
| SCHEMBL25836759 | 0.68 | ALDH1A1 (0.51) | ALDH1A1LMNACYP19A1PTGS2HSP90AB1 | |
| SCHEMBL25397946 | 0.68 | ALDH1A1 (0.60) | ALDH1A1LMNACYP19A1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | CYP51A1, OXA1L, O60361 | ALDH1A1 473/4885LMNA 1484/4885CYP19A1 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.