Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23038469 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL25836759 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL23376772 | 0.82 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL23376712 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL31006005 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL893141 | 0.75 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL17971112 | 0.72 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10475693 | 0.72 | MEN1 (0.67) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL25836764 | 0.71 | ALDH1A1 (0.51) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL28503072 | 0.71 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638140-A | Oxo-substituted compounds | 住友制药株式会社 | 2024-09-13 | — | — | CN | disclosed |
| CN-112135830-B | Oxo-substituted compounds | 住友制药株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2023-09-14 | — | — | US | disclosed |
| US-11702431-B2 | Oxo-substituted compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-18 | — | — | US | disclosed |
| CN-112135830-A | Oxo substituted compounds | 大日本住友制药株式会社 | 2020-12-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702431-B2 | Oxo-substituted compound | CYP51A1, OXA1L, O60361 | ALDH1A1 473/4885LMNA 1484/4885HPGD 461/4885 |
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | CYP51A1, OXA1L, O60361 | ALDH1A1 473/4885LMNA 1484/4885HPGD 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.