Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836758 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL23376712 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL23376772 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL23357710 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL25397946 | 0.76 | ALDH1A1 (0.60) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL893141 | 0.72 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL17971112 | 0.72 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10475693 | 0.72 | MEN1 (0.67) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL25836764 | 0.71 | ALDH1A1 (0.51) | ALDH1A1LMNAMEN1KMT2ACYP19A1 | |
| SCHEMBL28503072 | 0.70 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638140-A | Oxo-substituted compounds | 住友制药株式会社 | 2024-09-13 | — | — | CN | disclosed |
| CN-112135830-B | Oxo-substituted compounds | 住友制药株式会社 | 2024-06-14 | — | — | CN | disclosed |