Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.67 |
| ▸ | WEE1 | P30291 | 4/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 17/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.64 |
| ▸ | EGFR | P00533 | 6/20 | 0.64 |
| ▸ | ABL1 | P00519 | 4/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.62 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.62 |
| ▸ | PAK4 | O96013 | 1/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25400254 | 0.88 | FGFR1 (0.62) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL25399979 | 0.87 | FGFR1 (0.82) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL26257902 | 0.87 | FGFR1 (0.79) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL25399690 | 0.87 | FGFR1 (0.63) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL30618344 | 0.87 | FGFR1 (0.63) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL30618238 | 0.87 | FGFR1 (0.61) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL25396206 | 0.87 | FGFR1 (0.61) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL30618292 | 0.87 | WEE1 (0.61) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL25401372 | 0.87 | WEE1 (0.61) | SRCWEE1FGFR1PDGFRBPDGFRA | |
| SCHEMBL25399236 | 0.86 | FGFR1 (0.71) | SRCWEE1FGFR1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |