Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783737 | 0.80 | HTT (0.50) | SLC6A4HTR2AKCNH2RAB9AMAPK1 | |
| SCHEMBL25396490 | 0.78 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL3840431 | 0.76 | LTA4H (0.50) | SLC6A4HTR2AKCNH2SMN1; SMN2LMNA | |
| SCHEMBL3773755 | 0.76 | MEN1 (0.42) | SLC6A4HTR2AKCNH2NPC1RAB9A | |
| SCHEMBL25398816 | 0.76 | GAA (0.45) | POLBSMN1; SMN2KDM4ELMNAPTGS2 | |
| SCHEMBL5753110 | 0.75 | ALDH1A1 (0.54) | SLC6A4HTR2AKCNH2POLBESR1 | |
| SCHEMBL19534980 | 0.75 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2POLBESR1 | |
| SCHEMBL473944 | 0.73 | HSD17B10 (0.46) | SLC6A4HTR2AKCNH2POLBKDM4E | |
| SCHEMBL28301168 | 0.73 | LTA4H (0.56) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL8340513 | 0.73 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2POLBSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |