Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840431 | 0.89 | LTA4H (0.50) | LTA4HSLC6A4HTR2AKCNH2ALDH1A1 | |
| SCHEMBL7342450 | 0.87 | LTA4H (0.54) | LTA4HMTNR1AMTNR1BGPR55HSP90AA1 | |
| SCHEMBL11843492 | 0.83 | SLC6A4 (0.47) | LTA4HMTNR1AMTNR1BSLC6A4SLC6A2 | |
| SCHEMBL9349881 | 0.82 | DHODH (0.54) | LTA4HSLC6A4SLC6A2SLC6A3MAOB | |
| SCHEMBL11464397 | 0.82 | CA1 (0.53) | ALDH1A1 | |
| SCHEMBL3300286 | 0.81 | LTA4H (0.58) | LTA4HMTNR1AMTNR1BGPR55ALDH1A1 | |
| SCHEMBL11292183 | 0.81 | LTA4H (0.58) | LTA4HMTNR1AMTNR1BGPR55CYP11B1 | |
| SCHEMBL6159185 | 0.79 | LTA4H (0.56) | LTA4HMTNR1AMTNR1BGPR55CYP11B1 | |
| SCHEMBL30419864 | 0.79 | ALOX5 (0.66) | LTA4HMTNR1AMTNR1BHSP90AA1SLC6A2 | |
| SCHEMBL7116653 | 0.79 | MTNR1A (0.62) | LTA4HMTNR1AMTNR1BGPR55HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015952-B | Diaryl methane compound and preparation method and application thereof | 北京大学深圳研究生院 | 2022-08-19 | — | — | CN | disclosed |
| CN-110015952-A | Diarylmethanes class compound and its preparation method and application | 北京大学深圳研究生院 | 2019-07-16 | — | — | CN | disclosed |