SCHEMBL25399310

SCHEMBL25399310

Clc1cc(Br)c2c(c1)[nH]c1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 7/20 0.48
CCND1 P24385 7/20 0.48
CCNE2 O96020 6/20 0.48
CCNE1 P24864 6/20 0.48
CDK2 P24941 6/20 0.48
CAMK2B Q13554 5/20 0.48
CAMK2G Q13555 5/20 0.48
CAMK2D Q13557 5/20 0.48
CAMK2A Q9UQM7 5/20 0.48
PARP1 P09874 2/20 0.46
ALDH1A1 P00352 1/20 0.45
GPR3 P46089 1/20 0.45
HSD17B10 Q99714 1/20 0.45
GABRP O00591 3/20 0.44
GABRD O14764 3/20 0.44
GABRA1 P14867 3/20 0.44
GABRB1 P18505 3/20 0.44
GABRG2 P18507 3/20 0.44
GABRB3 P28472 3/20 0.44
GABRA5 P31644 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542026 0.83 CCNE2 (0.51) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL25399086 0.81 RHEB (0.37) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL17727817 0.79 PARP1 (0.58) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL28619358 0.79 ERCC5 (0.39) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL25397317 0.78 KIF11 (0.50) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL14951429 0.76 CRHBP (0.43) CDK4CCND1ALDH1A1GPR3HSD17B10
SCHEMBL29387190 0.76 ALDH1A1 (0.50) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL31728 0.76 ALDH1A1 (0.50) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL31518299 0.75 IDO1 (0.48) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL27290067 0.75 IDO1 (0.48) CDK4CCND1CCNE2CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010818-A Organic compound, and electronic component and electronic device using same 陕西莱特光电材料股份有限公司 2026-05-12 CN disclosed
US-20240209006-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, AND DISPLAY PANEL SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-06-27 US disclosed
CN-117440960-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-01-23 CN disclosed
WO-2023172110-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-09-14 WO disclosed
WO-2023172110-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209006-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, AND DISPLAY PANEL NR2E3, NR2C2, NR4A2 CDK4 495/4885CCND1 365/4885CCNE2 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.