SCHEMBL25399525

SCHEMBL25399525

BrCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29904659 0.98 KIF11 (0.55) KIF11
SCHEMBL5350718 0.98 KIF11 (0.55) KIF11
SCHEMBL21093254 0.98 KIF11 (0.55) KIF11
SCHEMBL17493269 0.94 KIF11 (0.59) KIF11
SCHEMBL4288415 0.85 KIF11 (0.63) KIF11
SCHEMBL18599373 0.80 KIF11 (0.57) KIF11
SCHEMBL25400195 0.80 KIF11 (0.74) KIF11
SCHEMBL5357811 0.78 KIF11 (0.55) KIF11
SCHEMBL8447104 0.78 KIF11 (0.55) KIF11
SCHEMBL22756327 0.78 KIF11 (0.55) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021055-A1 Asymmetric Piperazine-Based Cationic Lipids TRANSLATE BIO, INC. (US) 2026-01-22 US disclosed
WO-2025134071-A1 MALIC AND GLUTARIC ACID BASED IONIZABLE LIPIDS SANOFI (FR) 2025-06-26 WO disclosed
WO-2023198857-A1 \"GOOD\" BUFFER-BASED CATIONIC LIPIDS SANOFI (FR) 2023-10-19 WO disclosed
WO-2023178167-A1 ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS TRANSLATE BIO, INC. (US) 2023-09-21 WO disclosed
WO-2023178167-A1 ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS TRANSLATE BIO, INC. (US) 2023-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021055-A1 Asymmetric Piperazine-Based Cationic Lipids SGMS2, SPTLC2, SGMS1 KIF11 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.