SCHEMBL254038

SCHEMBL254038

C=C(C)C(=O)OCc1ccc(COC(=O)C(=C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 3/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
POLB P06746 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24019226 0.94 ALDH1A1 (0.46) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL16125663 0.94 ALDH1A1 (0.46) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL92326 0.94 MEN1 (0.53) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL15944747 0.94 ALDH1A1 (0.46) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL17791311 0.94 ALDH1A1 (0.46) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL10720993 0.92 ALDH1A1 (0.44) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL148297 0.92 MAOB (0.47) ALDH1A1TSHRMAPK1
SCHEMBL9554958 0.92 ALDH1A1 (0.44) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL4354853 0.92 ALDH1A1 (0.44) ALDH1A1TSHRKMT2AMEN1THRB
SCHEMBL13836458 0.91 KDM4E (0.49) ALDH1A1KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170176852-A1 PHOTO-IMPRINTING RESIN COMPOSITION, PHOTO-IMPRINTING RESIN FILM AND PATTERNING PROCESS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-22 US claimed
EP-2814523-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING A MULTI-ARM PEG MACROMER NOVARTIS AG (CH) 2016-04-06 EP claimed
US-9012581-B2 Ophthalmic and otorhinolaryngological device materials NOVARTIS AG (CH) 2015-04-21 US claimed
US-8900297-B2 Ophthalmic and otorhinolaryngological device materials NOVARTIS AG (CH) 2014-12-02 US claimed
EP-2470578-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS NOVARTIS AG (CH) 2014-11-12 EP claimed
US-20140213733-A1 Ophthalmic and Otorhinolaryngological Device Materials NOVARTIS AG (CH) 2014-07-31 US claimed
US-8728157-B2 Ophthalmic and otorhinolaryngological device materials NOVARTIS AG (CH) 2014-05-20 US claimed
US-20140024777-A1 Ophthalmic And Otorhinolaryngological Device Materials Containing An Alkylphenol Ethoxylate NOVARTIS AG (CH) 2014-01-23 US claimed
US-8574292-B2 Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate NOVARTIS AG (CH) 2013-11-05 US claimed
US-8293858-B1 Ophthalmic and otorhinolaryngological device materials containing a reactive NVP macromer NOVARTIS AG (CH) 2012-10-23 US claimed
EP-2192930-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE ALCON INC (CH) 2011-04-13 EP claimed
US-20110046258-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2011-02-24 US claimed
US-7888403-B2 soft foldable intraocular lenses with no glistenings or vacuoles when stored in water; monofunctional phenyl or alkylphenyl acrylate or acrylamide and difunctional acrylate or acrylamide monomers; a di- or tri-block acrylic macromer ALCON, INC. (CH) 2011-02-15 US claimed
US-7858672-B1 Methacrylic materials suitable for ophthalmic and otorhinolaryngological devices ALCON, INC. (CH) 2010-12-28 US claimed
US-7799845-B2 Ophthalmic and otorhinolaryngological device materials ALCON, INC. (CH) 2010-09-21 US claimed
US-20090093603-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 US claimed
US-20090093604-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 US claimed
US-20090093592-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 US claimed
US-20090088544-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE ALCON, INC. (CH) 2009-04-02 US claimed
US-20090088493-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYLPHENOL ETHOXYLATE ALCON, INC. (CH) 2009-04-02 US claimed