SCHEMBL15944747

SCHEMBL15944747

C=C(C)C(=O)OCc1ccc(CCc2ccc(COC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
THRB P10828 2/20 0.44
TSHR P16473 3/20 0.42
THRA P10827 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
KDM4E B2RXH2 1/20 0.38
F13A1 P00488 1/20 0.38
HSD17B10 Q99714 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17791311 1.00 ALDH1A1 (0.46) ALDH1A1THRBTSHRTHRAMEN1
SCHEMBL17701522 0.95 ALDH1A1 (0.42) ALDH1A1THRBTSHRTHRAMEN1
SCHEMBL254038 0.94 ALDH1A1 (0.50) ALDH1A1THRBTSHRMEN1KMT2A
SCHEMBL13783931 0.91 THRB (0.46) ALDH1A1THRBTSHRTHRAPOLB
SCHEMBL17791317 0.90 CYP1A2 (0.44) ALDH1A1THRBTSHRTHRAPOLB
SCHEMBL14329719 0.89 THRB (0.45) ALDH1A1THRBTSHRTHRAMEN1
SCHEMBL24019226 0.89 ALDH1A1 (0.46) ALDH1A1THRBTSHRMEN1KMT2A
SCHEMBL92326 0.89 MEN1 (0.53) ALDH1A1THRBTSHRMEN1KMT2A
SCHEMBL16125663 0.89 ALDH1A1 (0.46) ALDH1A1THRBTSHRMEN1KMT2A
SCHEMBL10665718 0.88 THRB (0.53) ALDH1A1THRBTSHRTHRAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170349829-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2017-12-07 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-9810938-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-20170306231-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-10-26 US disclosed
US-20170260451-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-09-14 US disclosed
US-20170253800-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-09-07 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-8980384-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2015-03-17 US disclosed
US-20150060733-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2015-03-05 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-20150028257-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2015-01-29 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
US-20140361220-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-12-11 US disclosed
US-8906472-B2 Nematic liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2014-12-09 US disclosed
US-20140231712-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2014-08-21 US disclosed
US-20140226119-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2014-08-14 US disclosed