Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25404170 | 0.86 | TP53 (0.64) | TP53NPC1RAB9AKDM4EMAPT | |
| SCHEMBL25189182 | 0.78 | RIOK2 (0.60) | TP53NPC1RAB9AKDM4EMAPT | |
| SCHEMBL25402398 | 0.78 | F2 (0.59) | TP53NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL25407042 | 0.77 | TP53 (0.65) | TP53NPC1RAB9AKDM4EMAPT | |
| SCHEMBL25405258 | 0.77 | ALDH1A1 (0.66) | TP53NPC1RAB9AKDM4EMAPT | |
| SCHEMBL25404025 | 0.76 | NPC1 (0.53) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25405854 | 0.75 | RAB9A (0.67) | TP53NPC1RAB9AKDM4EMAPT | |
| SCHEMBL3932265 | 0.75 | RIOK2 (0.57) | TP53ALDH1A1SMN1; SMN2RIOK2MAPK10 | |
| SCHEMBL25406525 | 0.75 | KDR (0.71) | TP53ALDH1A1RIOK2MAPK10GSK3A | |
| SCHEMBL25402019 | 0.74 | NR3C2 (0.67) | TP53ALDH1A1SMN1; SMN2RIOK2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | claimed |
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |