Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403958 | 0.96 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10TDP1STING1 | |
| SCHEMBL25403667 | 0.81 | HTT (0.49) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL25402636 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL31070648 | 0.80 | GABRA1 (0.57) | KDM4ESTING1 | |
| SCHEMBL25402669 | 0.80 | MEN1 (0.48) | KDM4EALDH1A1STING1MAPTKMT2A | |
| SCHEMBL30593250 | 0.79 | TAAR1 (0.65) | KDM4EALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL25407518 | 0.79 | TAAR1 (0.65) | KDM4EALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL25403976 | 0.78 | LMNA (0.65) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL25405760 | 0.78 | KMT2A (0.65) | KDM4EALDH1A1MAPTKMT2AMAPK1 | |
| SCHEMBL25404693 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |