Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674580 | 0.75 | NLRP3 (0.42) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL22012365 | 0.71 | NLRP3 (0.45) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL6867779 | 0.71 | TRPA1 (0.33) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL19791962 | 0.69 | TRPA1 (0.32) | NLRP3ALDH1A1 | |
| SCHEMBL20681025 | 0.69 | TRPA1 (0.32) | NLRP3ALDH1A1 | |
| SCHEMBL30852987 | 0.68 | NLRP3 (0.63) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL21646719 | 0.67 | NLRP3 (0.42) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL19505705 | 0.67 | NLRP3 (0.46) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL20713466 | 0.67 | NLRP3 (0.54) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL20635326 | 0.67 | NLRP3 (0.42) | NLRP3ALDH1A1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156311-A1 | PROCESSES FOR THE PREPARATION OF 1,2,3,5,6,7-HEXAHYDRO-S-INDACENE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-24 | — | — | WO | disclosed |