⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14823458 | 0.71 | — | — | |
| SCHEMBL25342190 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL25342195 | 0.66 | POLB (0.43) | — | |
| SCHEMBL24690873 | 0.64 | — | — | |
| SCHEMBL15230001 | 0.64 | — | — | |
| SCHEMBL5336862 | 0.60 | NOS1 (0.53) | — | |
| SCHEMBL24014938 | 0.59 | — | — | |
| SCHEMBL23092922 | 0.58 | TDO2 (0.56) | — | |
| SCHEMBL1476214 | 0.57 | — | — | |
| SCHEMBL18553109 | 0.55 | TP53 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509423-B2 | Compound, aldehyde dehydrogenase 2 activating agent, pharmaceutical composition, and therapeutic and/or prophylactic drug | ALCHEMEDICINE, INC. (JP) | 2025-12-30 | — | — | US | disclosed |
| US-20230295091-A1 | Compound, Aldehyde Dehydrogenase 2 Activating Agent, Pharmaceutical Composition, and Therapeutic and/or Prophylactic Drug | ALCHEMEDICINE, INC. (JP) | 2023-09-21 | — | — | US | disclosed |
| US-20230295091-A1 | Compound, Aldehyde Dehydrogenase 2 Activating Agent, Pharmaceutical Composition, and Therapeutic and/or Prophylactic Drug | ALCHEMEDICINE, INC. (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-4238964-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | Alchemedicine, Inc. (JP) | 2023-09-06 | — | — | EP | disclosed |
| EP-4238964-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | Alchemedicine, Inc. (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116348449-A | Compounds, acetaldehyde dehydrogenase 2 activators, pharmaceutical compositions, and therapeutic and/or prophylactic agents | 亚克医药株式会社 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022092310-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | 株式会社アークメディスン | 2022-05-05 | — | — | WO | disclosed |