Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465049 | 0.84 | TAS2R14 (0.43) | NOTUMCES2AKR1C3AKR1C2RXRA | |
| SCHEMBL31697325 | 0.84 | TAS2R14 (0.43) | NOTUMCES2AKR1C3AKR1C2RXRA | |
| SCHEMBL9465091 | 0.82 | DGAT1 (0.41) | NOTUMCES2SOS1TMPRSS4SMN1; SMN2 | |
| SCHEMBL23887001 | 0.82 | HTT (0.46) | NOTUMCES2TMPRSS4SMN1; SMN2AKR1C3 | |
| SCHEMBL18299626 | 0.81 | P2RX1 (0.44) | CES2TMPRSS4AKR1C3AKR1C2MAPT | |
| SCHEMBL5224905 | 0.81 | SOS1 (0.55) | NOTUMCES2SOS1TMPRSS4MAPT | |
| SCHEMBL31396446 | 0.79 | NOTUM (0.41) | NOTUMCES2SOS1RXFP1RXRA | |
| SCHEMBL18243875 | 0.79 | DDR1 (0.45) | CES2TMPRSS4SMN1; SMN2MAPTP2RX1 | |
| SCHEMBL23326539 | 0.78 | PTPN5 (0.51) | TMPRSS4AKR1C3AKR1C2MAPTP2RX1 | |
| SCHEMBL25406281 | 0.78 | MLYCD (0.41) | NOTUMCES2SOS1P2RX1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |