Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1535756 | 0.96 | CA12 (0.40) | CA12CA9CA1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL6265698 | 0.94 | CA12 (0.39) | CA12CA9CA1ALDH1A1ALDH2 | |
| SCHEMBL1713038 | 0.94 | CA12 (0.41) | CA12CA9CA1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL25405638 | 0.92 | CA12 (0.38) | CA12CA9CA1ALDH1A1ALDH2 | |
| Iodide SCHEMBL7030478 | 0.91 | CA12 (0.40) | CA12CA9CA1ALDH1A1ALDH2 | |
| Fluoride Ion SCHEMBL5446663 | 0.91 | CA12 (0.40) | CA12CA9CA1ALDH1A1ALDH2 | |
| Bromide SCHEMBL6155069 | 0.91 | CA12 (0.40) | CA12CA9CA1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL25405687 | 0.90 | CA12 (0.42) | CA12CA9CA1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL14862018 | 0.90 | CA12 (0.44) | CA12CA9CA1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL29466158 | 0.89 | CA12 (0.34) | CA12CA9CA1ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | claimed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | MRPS22, MRPS23, SRM | CA12 1733/4885CA9 2048/4885CA1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.