Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.57 |
| ▸ | PRKACA | P17612 | 2/20 | 0.57 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | PRKX | P51817 | 2/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PAK4 | O96013 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | AKT2 | P31751 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405435 | 0.85 | MAPK1 (0.59) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL30341563 | 0.85 | MAPK1 (0.59) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25407128 | 0.84 | ROCK2 (0.57) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL28015856 | 0.83 | ALDH1A1 (0.60) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25406458 | 0.78 | MAPK1 (0.48) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25405503 | 0.77 | ROCK1 (0.59) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25405796 | 0.75 | KDM4E (0.51) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25406342 | 0.75 | CYP1A2 (0.45) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25405587 | 0.74 | ROCK1 (0.59) | ROCK2MAPK1ROCK1PRKACAGSK3A | |
| SCHEMBL25406737 | 0.74 | MAPK1 (0.51) | ROCK2MAPK1ROCK1PRKACAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-27 | — | — | US | disclosed |
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-21 | — | — | US | disclosed |
| EP-4161914-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | PNPO, CBR3, HPD | ROCK2 2871/4885MAPK1 1340/4885ROCK1 3123/4885 |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | CBR1, CBR3, NOX1 | ROCK2 3738/4885MAPK1 855/4885ROCK1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.