SCHEMBL25407

SCHEMBL25407

[CH2]c1ccc(Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2096471 0.90 ALDH1A1 (0.55)
SCHEMBL10439485 0.83 CYP2C19 (0.50)
SCHEMBL3098976 0.83 CYP2A6 (0.42)
SCHEMBL5540429 0.83 MAPT (0.58)
SCHEMBL147275 0.78
SCHEMBL18508 0.78
SCHEMBL21518322 0.74
Methane SCHEMBL21489530 0.74 CYP2A6 (0.89)
SCHEMBL3138002 0.74
SCHEMBL9496102 0.74 CYP2A6 (0.89)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9261 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
CN-113754569-B Intermediate compound and preparation method and application thereof 四川国为制药有限公司 2024-07-02 CN claimed
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
CN-118239883-A Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor 江苏联环药业股份有限公司 2024-06-25 CN claimed
CN-118206748-A PCB electroplating additive and preparation method thereof 广东利尔化学有限公司 2024-06-18 CN claimed
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
US-4150227-A Process for the production of basic substituted alkyl theophylline DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-04-17 US claimed
US-4145540-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-03-20 US claimed
US-4098897-A ANTI BACTERIAL AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US claimed
US-4078067-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-03-07 US claimed
US-4078068-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-03-07 US claimed
US-4076826-A ANTIBIOTIC MERCK & CO., INC. (US) 1978-02-28 US claimed
US-4029712-A OXIDATION OF MERCAPTAL SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-06-14 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3933800-A O-SUBSTITUTED OXIMES, MICROBIOCIDES GRUPPO LEPETIT S.P.A. (IT) 1976-01-20 US claimed
US-3931178-A ANTIHISTAMINES SANDOZ INC. (US) 1976-01-06 US claimed