Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231097 | 1.00 | SLC7A5 (0.48) | SLC7A5GFPT1SLC1A3SLC1A2PSMB5 | |
| SCHEMBL1768507 | 0.88 | GFPT1 (0.46) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL28095721 | 0.88 | GFPT1 (0.46) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL25410006 | 0.86 | GFPT1 (0.45) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL25410008 | 0.86 | GFPT1 (0.45) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL5082612 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2GRIK1SLC1A1 | |
| SCHEMBL5082599 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2GRIK1SLC1A1 | |
| SCHEMBL1768908 | 0.79 | GFPT1 (0.49) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL1768905 | 0.79 | GFPT1 (0.49) | SLC7A5GFPT1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL27761217 | 0.79 | CYP2D6 (0.43) | PSMB5CYP2D6CYP2C19TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170216-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-20230295259-A1 | Conjugated Hepcidin Mimetics | PROTAGONIST THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295259-A1 | Conjugated Hepcidin Mimetics | HAMP, VIP, HDGF | SLC7A5 927/4885GFPT1 1286/4885SLC1A3 2450/4885 |
| US-20250170216-A1 | CONJUGATED HEPCIDIN MIMETICS | HAMP, VIP, HDGF | SLC7A5 930/4885GFPT1 1484/4885SLC1A3 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.