Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358942 | 0.77 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7940135 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL20266963 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL25406642 | 0.73 | GAA (0.48) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL8349565 | 0.72 | CA2 (0.54) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7956828 | 0.71 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5905934 | 0.71 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL3131059 | 0.71 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL30157536 | 0.71 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5251939 | 0.70 | KMT2A (0.49) | ALDH1A1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481801-B1 | INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME | UNIV ARIZONA (US) | 2023-09-06 | — | — | EP | disclosed |