Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 7/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | SOD3 | P08294 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729661 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1MEN1KMT2A | |
| SCHEMBL13976317 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1MEN1KMT2A | |
| SCHEMBL13976316 | 0.89 | GNAI3 (0.43) | GNAO1GNAI3GNAI1 | |
| SCHEMBL15805642 | 0.89 | GNAI3 (0.43) | GNAO1GNAI3GNAI1 | |
| SCHEMBL26939746 | 0.88 | GNAO1 (0.41) | GNAO1GNAI3GNAI1MEN1KMT2A | |
| SCHEMBL20738848 | 0.85 | CARM1 (0.47) | GNAO1GNAI3GNAI1ALDH1A1 | |
| SCHEMBL19867108 | 0.85 | CARM1 (0.47) | GNAO1GNAI3GNAI1ALDH1A1 | |
| SCHEMBL19101393 | 0.85 | CARM1 (0.47) | GNAO1GNAI3GNAI1ALDH1A1 | |
| SCHEMBL20355889 | 0.84 | GNAI3 (0.40) | GNAO1GNAI3GNAI1TLR8TLR7 | |
| SCHEMBL18799880 | 0.84 | GNAI3 (0.40) | GNAO1GNAI3GNAI1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137550-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF COVID-19 | PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) | 2023-07-27 | — | — | WO | disclosed |