Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105246 | 0.94 | EPHX1 (0.61) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL21064585 | 0.90 | PTGS1 (0.57) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL13718987 | 0.89 | EPHX1 (0.56) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL10580349 | 0.85 | EPHX1 (0.51) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL5018743 | 0.83 | PTGS1 (0.55) | ALOX5PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL25693884 | 0.83 | LMNA (0.61) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL24827555 | 0.81 | TRPA1 (0.50) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL8745472 | 0.81 | TAAR1 (0.59) | PLA2G10PLA2G2A | |
| SCHEMBL6764390 | 0.81 | TAAR1 (0.59) | PLA2G10PLA2G2A | |
| SCHEMBL9392575 | 0.81 | TAAR1 (0.59) | PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459565-B1 | SAXITOXIN DERIVATIVES, METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | UNIV LELAND STANFORD JUNIOR (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2010129864-A9 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2010129864-A2 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-11-11 | — | — | WO | disclosed |