Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20034810 | 0.98 | FAAH (0.41) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL21016081 | 0.84 | FAAH (0.45) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18159035 | 0.83 | FAAH (0.38) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL22872813 | 0.83 | FAAH (0.44) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26691656 | 0.83 | FAAH (0.44) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14996240 | 0.82 | TSHR (0.43) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20034909 | 0.82 | FAAH (0.37) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23589915 | 0.81 | FAAH (0.42) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL21015937 | 0.81 | FAAH (0.42) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23589700 | 0.81 | FAAH (0.42) | FAAHKMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459565-B1 | SAXITOXIN DERIVATIVES, METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | UNIV LELAND STANFORD JUNIOR (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9174999-B2 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| WO-2010129864-A9 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2010129864-A2 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | INA, SCN3A, SCN9A | FAAH 2914/4885KMT2A 1792/4885SMN1; SMN2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.