Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25411828 | 1.00 | GAA (0.39) | GAAALDH1A1NLRP3CYP3A4CYP2D6 | |
| SCHEMBL25411871 | 0.87 | ALDH1A1 (0.39) | GAAALDH1A1NLRP3CAPN1MAPT | |
| SCHEMBL25411864 | 0.87 | ALDH1A1 (0.39) | GAAALDH1A1NLRP3CAPN1MAPT | |
| SCHEMBL26308101 | 0.87 | ALDH1A1 (0.40) | GAAALDH1A1NLRP3CAPN1MAPT | |
| SCHEMBL25410730 | 0.83 | HTR6 (0.40) | ALDH1A1NLRP3MAPTSMN1; SMN2CMA1 | |
| SCHEMBL25410726 | 0.83 | HTR6 (0.40) | ALDH1A1NLRP3MAPTSMN1; SMN2CMA1 | |
| SCHEMBL25413587 | 0.81 | GAA (0.44) | GAAALDH1A1NLRP3CYP3A4CYP2C9 | |
| SCHEMBL25413591 | 0.81 | GAA (0.44) | GAAALDH1A1NLRP3CYP3A4CYP2C9 | |
| SCHEMBL25411450 | 0.81 | ALDH1A1 (0.40) | GAAALDH1A1NLRP3CYP2C9CYP2C19 | |
| SCHEMBL25411441 | 0.81 | ALDH1A1 (0.40) | GAAALDH1A1NLRP3CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | MISSISSIPPI STATE UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278959-A1 | Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization | INMT, IDO2, WEE2 | GAA 4101/4885ALDH1A1 3453/4885NLRP3 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.