Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387500 | 0.88 | LMNA (0.49) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL18639389 | 0.86 | LMNA (0.46) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL30135763 | 0.83 | SMN1; SMN2 (0.46) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL5500990 | 0.81 | LMNA (0.56) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL31111887 | 0.81 | GAA (0.49) | LMNAPOLBSMN1; SMN2ATMALDH1A1 | |
| SCHEMBL30002152 | 0.78 | SMN1; SMN2 (0.50) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL30177254 | 0.78 | SMN1; SMN2 (0.43) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL30177290 | 0.78 | SMN1; SMN2 (0.43) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL8821262 | 0.78 | LMNA (0.51) | LMNAPOLBSMN1; SMN2ATMHPGD | |
| SCHEMBL31338431 | 0.78 | SMN1; SMN2 (0.44) | LMNAPOLBSMN1; SMN2ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |