Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013395 | 0.89 | LMNA (0.48) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL30177286 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL30177290 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL30135763 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL30177306 | 0.81 | MGLL (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL30177247 | 0.80 | LMNA (0.44) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL23859720 | 0.79 | LMNA (0.49) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL31111887 | 0.78 | GAA (0.49) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL25412507 | 0.78 | LMNA (0.43) | SMN1; SMN2LMNAPOLBALDH1A1GBA2 | |
| SCHEMBL30177277 | 0.77 | MGLL (0.46) | OPRD1OPRK1BCHECHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126852-A1 | AZASPIROCYCLES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |