Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002152 | 0.88 | SMN1; SMN2 (0.50) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL25412507 | 0.88 | LMNA (0.43) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL5500990 | 0.86 | LMNA (0.56) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL30177282 | 0.80 | LMNA (0.50) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL30136018 | 0.79 | LMNA (0.55) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL30177286 | 0.79 | SMN1; SMN2 (0.49) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL29991215 | 0.79 | LMNA (0.46) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL21409258 | 0.78 | LMNA (0.54) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL12468857 | 0.78 | SMN1; SMN2 (0.50) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL30225407 | 0.78 | SMN1; SMN2 (0.54) | LMNAPOLBSMN1; SMN2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022028547-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2022-02-10 | — | — | WO | disclosed |