Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880219 | 0.97 | HRH2 (0.51) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL19063181 | 0.95 | HRH2 (0.45) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL254771 | 0.94 | HRH2 (0.45) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL15500299 | 0.93 | HRH2 (0.43) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL29331205 | 0.92 | HRH2 (0.46) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL19064892 | 0.92 | HRH2 (0.49) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL22259848 | 0.92 | HRH2 (0.46) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL19052146 | 0.91 | HRH2 (0.47) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL19976544 | 0.91 | HRH2 (0.42) | HRH2MLNRNR1I2PGRADRB1 | |
| SCHEMBL19052147 | 0.91 | HRH2 (0.44) | HRH2MLNRNR1I2PGRADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230365614-A1 | FLUORESCENT POLYMERASE ENZYME SUBSTRATES HAVING PROTEIN SHIELDS | PACIFIC BIOSCIENCESOF CALIFORNIA INC (US) | 2023-11-16 | — | — | US | disclosed |
| US-11718639-B2 | Fluorescent polymerase enzyme substrates having protein shields | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| US-11359235-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-11203689-B2 | Protected dye-labeled reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-20210347808-A1 | FLUORESCENT POLYMERASE ENZYME SUBSTRATES HAVING PROTEIN SHIELDS | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2021-11-11 | — | — | US | disclosed |
| US-11014958-B2 | Fluorescent polymerase enzyme substrates having protein shields | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20210147928-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20200299319-A1 | PROTECTED DYE-LABELED REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11359235-B2 | Modified nucleotide reagents | POLL, POLN, POLM | HRH2 4834/4885MLNR 1588/4885NR1I2 4442/4885 |
| US-12037641-B2 | Modified nucleotide reagents | POLL, POLN, POLM | HRH2 4834/4885MLNR 1588/4885NR1I2 4442/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | HRH2 4138/4885MLNR 1127/4885NR1I2 3469/4885 |
| US-20210347808-A1 | FLUORESCENT POLYMERASE ENZYME SUBSTRATES HAVING PROTEIN SHIELDS | POLL, POLN, POLA1 | HRH2 4819/4885MLNR 3632/4885NR1I2 3879/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | HRH2 4138/4885MLNR 1127/4885NR1I2 3469/4885 |
| US-20230365614-A1 | FLUORESCENT POLYMERASE ENZYME SUBSTRATES HAVING PROTEIN SHIELDS | POLL, POLN, POLA1 | HRH2 4819/4885MLNR 3632/4885NR1I2 3879/4885 |
| US-20210147928-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | POLL, POLN, POLB | HRH2 4767/4885MLNR 1617/4885NR1I2 4449/4885 |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | POLL, POLN, POLB | HRH2 4767/4885MLNR 1617/4885NR1I2 4449/4885 |
| US-20200299319-A1 | PROTECTED DYE-LABELED REAGENTS | POLL, POLB, POLM | HRH2 4810/4885MLNR 2714/4885NR1I2 4167/4885 |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | ALKBH1, ALKBH5, ALKBH3 | HRH2 4776/4885MLNR 1884/4885NR1I2 4436/4885 |
| US-11203689-B2 | Protected dye-labeled reagents | POLL, POLB, POLM | HRH2 4810/4885MLNR 2714/4885NR1I2 4167/4885 |
| US-11718639-B2 | Fluorescent polymerase enzyme substrates having protein shields | POLL, POLN, POLA1 | HRH2 4819/4885MLNR 3632/4885NR1I2 3879/4885 |
| US-11014958-B2 | Fluorescent polymerase enzyme substrates having protein shields | POLL, POLN, POLA1 | HRH2 4819/4885MLNR 3632/4885NR1I2 3879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.