Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25412445 | 0.91 | P2RX7 (0.36) | P2RX7P2RX3MAPTTP53CYP1A2 | |
| SCHEMBL25411495 | 0.89 | P2RX7 (0.38) | P2RX7P2RX3MAPTTP53CYP1A2 | |
| SCHEMBL25410665 | 0.86 | P2RX7 (0.36) | P2RX7P2RX3MAPTCYP1A2CYP3A4 | |
| SCHEMBL25409041 | 0.86 | P2RX7 (0.36) | P2RX7P2RX3MAPTTP53CYP1A2 | |
| SCHEMBL26312738 | 0.84 | CYP1A2 (0.40) | P2RX7P2RX3MAPTTP53CYP1A2 | |
| SCHEMBL30305525 | 0.84 | CYP1A2 (0.40) | P2RX7P2RX3MAPTTP53CYP1A2 | |
| SCHEMBL30451183 | 0.84 | TSHR (0.39) | P2RX7MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30305424 | 0.80 | TGFBR1 (0.37) | P2RX7P2RX3CYP1A2CYP3A4TSHR | |
| SCHEMBL23985112 | 0.80 | TGFBR1 (0.37) | P2RX7P2RX3CYP1A2CYP3A4TSHR | |
| SCHEMBL30855840 | 0.76 | CYP1A2 (0.39) | P2RX3MAPTTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171444-A1 | PI3Ka INHIBITORS | PIKAVATION THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| WO-2023168378-A1 | PI3KA INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023168378-A1 | PI3KA INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171444-A1 | PI3Ka INHIBITORS | PIK3CA, PIK3C2A, PIK3R5 | P2RX7 3269/4885P2RX3 3141/4885MAPT 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.