SCHEMBL25415100

SCHEMBL25415100

CNC(=S)NNC(=O)C1(c2cc(Cl)nc(Cl)c2)CC(C)C1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.35
▸ GAA P10253 7/20 0.34
▸ LMNA P02545 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ RAB9A P51151 2/20 0.31
▸ TDP1 Q9NUW8 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30872133 0.87 ALDH1A1 (0.35) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL31459164 0.86 ALDH1A1 (0.38) ALDH1A1GAALMNARAB9A
SCHEMBL25310389 0.82 ALDH1A1 (0.35) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL25309898 0.82 ALDH1A1 (0.35) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL31459168 0.82 ALDH1A1 (0.36) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL31251405 0.82 ALDH1A1 (0.33) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL31458865 0.80 ALDH1A1 (0.32) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL25262631 0.80 LMNA (0.34) ALDH1A1GAALMNAKMT2AMEN1
SCHEMBL31458993 0.79 MEN1 (0.38) ALDH1A1GAAKMT2AMEN1MAPK1
SCHEMBL31459244 0.79 S1PR2 (0.34) LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2025-10-02 — — US disclosed
EP-4490152-A1 ACTIVATORS OF EFFECTOR T CELLS Orum Therapeutics Inc. (KR) 2025-01-15 — — EP disclosed
WO-2023170608-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2023-09-14 — — WO disclosed
WO-2023170608-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2023-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS CBLB, CBL, CBLC ALDH1A1 4311/4885GAA 199/4885LMNA 3531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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