Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25415100 | 0.87 | ALDH1A1 (0.35) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL30872137 | 0.79 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL31458968 | 0.78 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL31251405 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL31459168 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL25311599 | 0.76 | KMT2A (0.40) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL30153227 | 0.76 | KMT2A (0.40) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL31459286 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL31737974 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL31459164 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |